Kirkland Signature Glucosamine HCI with MSM Review

Editors' rating:





Unsurprisingly, the product garners good consumer reviews and this is probably due to the attractive pricing as much as it is thanks to the efficacy. The daily serving of glucosamine and MSM is above average.

Kirkland Signature Glucosamine HCI with MSM Review

Joint pain affects almost everyone at some point in their lives, whether as a result of physical injury, illness or aging. Because joint pain is such a universal issue, there is a litany of supplements available. Today we review one of them called Kirkland Signature Glucosamine with MSM. Glucosamine and MSM are two critical ingredients in alleviating joint pain and are often found in supplements treating joint ailments.

A joint is found where two bones meet and are surrounded by cartilage and connective tissue. Typically, the symptoms for joint health issues involve inflammation, pain and loss of mobile function. In almost all cases, this is due to bone abrasion when the cartilage holding the joints together is torn or when the connective tissue is worn. It results in not enough lubrication in the joint. A typical joint-related disease is arthritis in all its forms.

Kirkland backs its product as being able to help you attain maximum flexibility, increased motion range and joint lubrication. According to the manufacturer, it also helps maintain healthy, strong cartilage and connective tissue.


Each serving of two tablets contains:

  • Glucosamine Hydrochloride – 1500 mg
  • MSM – 1500 mg
  • hydroxypropyl methylcellulose
  • modified corn starch
  • titanium dioxide
  • polyethylene glycol
  • glycerin, magnesium silicate
  • hydroxypropyl cellulose
  • silicon dioxide
  • magnesium stearate
  • boron glycinate

The active ingredients are the first two, while the rest make up the capsule. Glucosamine is vital to joint health. Without glucosamine, everyday movements and tasks would be very difficult and painful. The body needs glucosamine to make certain proteins and fats necessary for vital tissues, such as cartilage. As a result, it is critical for healthy joints, tendons and ligaments. In addition, it is also an ingredient in the fluids surrounding the joints. These absorb impact and lubricate the joints.

MSM, in supplement form, is artificially made. So vital is this sulfur-based compound, that it is the fourth most commonly occurring mineral in the body. It lowers inflammation, improves immunity, boosts energy and maintains and repairs bodily tissue. It is often found in green leafy vegetables in its natural state. Most supplements contain slightly less MSM, so this is an above-average dose.

Depending on the severity of the joint issue, the product should live up to its claims although the formulation probably could have benefited from additional ingredients that fight inflammation.


Take two tablets a day with food and water. Consult a physician before administering a dose to minors. Also obtain medical advice if you are pregnant, breastfeeding or are on chronic medication.


One bottle of 375 capsules costs $14.49 on the product website. This is a good price for a six-and-a-half month’s supply.


The manufacturer states that your money will be refunded if you are not completely happy with your purchase. However, no further details are given such as how long you have to return the bottle, if more than one can be returned and if only unopened products may be returned.

Kirkland Signature Extra Strength Glucosamine HCI with MSM Review – Conclusion

Unsurprisingly, the product garners good consumer reviews and this is probably due to the attractive pricing as much as it is thanks to the efficacy. The daily serving of glucosamine and MSM is above average. However, the product is missing other key anti inflammatories and notably, is missing chondroitin. The product is gluten-free and soy-free.

Although other supportive ingredients could have been added to help bioavailability and to support the working of the key ingredients, there is no reason why it should not bring relief from moderate joint ailments. A big factor to consider is the lack of a clear returns policy though. Only embark on this product once you have contacted the manufacturer to find out how long you have to return it. It could be that your condition is chondroitin-related, in which case you will need to use this for longer before seeing any improvement. It is also a pity that the manufacturer has not provided a time frame for when you can expect to feel relief, as this would have increased the confidence in this product.

Concise, honest reporting from Authority Reports.


Pauline RN, BSN, MSN, works as an emergency room nurse and has seen it all over her 20 year career. She is extremely dedicated to her job and is a member of the California Emergency Nurses Association.A strong believer in balanced eating and regular exercise, Pauline enjoys trying out new recipes and participating in Mud Runs with her partner. Protection Status

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